health

HPV protection may require fewer shots

NEWS IN BRIEF — Posted May 13, 2013

Print  |   Email  |   Respond  |   Reprints  |   Like Facebook  |   Share Twitter  |   Tweet Linkedin

Two doses of the human papillomavirus vaccine might offer a similar level of protection for young women as three doses, said a study in the May 1 issue of The Journal of the American Medical Association.

Researchers found that females who received two doses in six months had similar immune responses to HPV-16 and HPV-18 as girls who got three doses during the same period. Those two genotypes account for 70% of cervical cancer cases in the U.S., said the Centers for Disease Control and Prevention.

But the study authors said more data are needed on the duration of protection of two doses before reduced-doses schedules can be recommended (link).

Each year, an estimated 12,000 U.S. women are diagnosed with cervical cancer, and about 4,000 die of the disease, according to the CDC. To help prevent such deaths, the agency recommends that 11- and 12-year-old girls and boys receive three doses of the HPV vaccine.

Barriers to completing the immunization series in the U.S. and other countries include the number of recommended doses and the high cost of the vaccine, the study authors said.

Researchers examined data between August 2007 and February 2011 on 830 Canadian females ages 9 to 26 who had four or fewer sexual partners in their lifetimes. Participants were randomized to receive either two or three vaccine doses during a six-month period. Their antibody levels were measured at the start of the study and then at 7, 18, 24 and 36 months.

The study was published in a JAMA theme issue on child health, which included reports on vitamin D and the impact of early childhood adversity on a youth’s health and adult life.

Back to top


ADVERTISEMENT

ADVERTISE HERE


Featured
Read story

Confronting bias against obese patients

Medical educators are starting to raise awareness about how weight-related stigma can impair patient-physician communication and the treatment of obesity. Read story


Read story

Goodbye

American Medical News is ceasing publication after 55 years of serving physicians by keeping them informed of their rapidly changing profession. Read story


Read story

Policing medical practice employees after work

Doctors can try to regulate staff actions outside the office, but they must watch what they try to stamp out and how they do it. Read story


Read story

Diabetes prevention: Set on a course for lifestyle change

The YMCA's evidence-based program is helping prediabetic patients eat right, get active and lose weight. Read story


Read story

Medicaid's muddled preventive care picture

The health system reform law promises no-cost coverage of a lengthy list of screenings and other prevention services, but some beneficiaries still might miss out. Read story


Read story

How to get tax breaks for your medical practice

Federal, state and local governments offer doctors incentives because practices are recognized as economic engines. But physicians must know how and where to find them. Read story


Read story

Advance pay ACOs: A down payment on Medicare's future

Accountable care organizations that pay doctors up-front bring practice improvements, but it's unclear yet if program actuaries will see a return on investment. Read story


Read story

Physician liability: Your team, your legal risk

When health care team members drop the ball, it's often doctors who end up in court. How can physicians improve such care and avoid risks? Read story